Human evidence
We prioritize clinically relevant human data over marketing claims.
Independent supplement buying guides
Compare supplements by evidence, limits, and real-world use.
Independent guides that show what is worth buying, what is overhyped, and where the evidence actually stops.
- Evidence cited
- Evidence strength shown
- Limitations included
- MD review where scoped
Independent editorial siteNo paid rankings
Most useful first read
Why readers can trust our guides
Safety limits
We flag medication context, dose concerns, and where evidence stops.
Real-world use
We explain who a supplement may help, who should skip it, and what to compare before buying.
Public accountability
Errors are corrected and logged publicly, not quietly edited.
Free evidence tools
Label scanner
Photograph the Supplement Facts panel and compare each dose to published trial floors.
Barcode scanner
Scan or type the bottle barcode and we prefill the panel from the NIH Dietary Supplement Label Database.
Interaction concerns
Physician-reviewed medication + supplement pairs, graded from major to caution. Never a safety clearance.
Clinical dose registry
Trial dose floors and NIH DSLD market medians, with a free JSON dataset for reuse.
Magnesium elemental calculator
Convert compound milligrams to elemental magnesium by salt form before you buy.
Pause before labs
Hair gummies can fake thyroid. Creatine can fake creatinine. Check before the draw.
Editorialreview process
Written and edited by Daniel Hart
Our guides are written by science communications editor and checked against cited human evidence, safety limitations, and product claims.
Medical review: Natallia Kalistratava, MD(where guides are clinically scoped)
Daniel Hart
Science Communications Editor
Best starting points by situation
- On GLP-1 medication?Start with fiber, protein, creatine, electrolytes, and muscle-loss support.
- Comparing “natural Ozempic” claims?Read why berberine is not an Ozempic replacement.
- Hair shedding after weight loss?Compare supplement support vs proven treatments.
- SSRI sexual side effects?See what supplement evidence actually exists for antidepressant-induced ED.
- Longevity supplement shopping?Separate promising compounds from expensive hype.
- Evaluating a supplement label?Run the 90-second checklist before you buy — form, dose, certifier, additives, cost per day.
- Need label math or trial arithmetic?8 free calculators — blend floors, NNT, protein targets, magnesium elemental, metformin MUI, and more.
- Winter blues or seasonal low mood?Light therapy first, melatonin as a chronobiotic (not a sleeping pill), saffron for mood — what the trials actually show.
High-intent buying guides
Best GLP-1 Companion Supplements 2026: Practical Framework
GLP-1 companion supplements for Ozempic/Wegovy/Mounjaro: protein, fiber, electrolytes first. Skip fat burners and natural GLP-1 hype.
GLP-1 Protein Powders: What Won't Upset Your Stomach
Ozempic/Wegovy protein powder guide: whey concentrate for most, isolate if dairy bothers you, clear whey, plant protein. Gut-friendly, evidence-based.
Orforglipron vs Semaglutide (Ozempic): 2026 Comparison
Orforglipron (Foundayo) vs Ozempic and Wegovy: weight-loss and HbA1c data, side effects, list prices, empty-stomach dosing, and who should skip both.
Akkermansia and GLP-1 Probiotics: Evidence Check
GLP-1 probiotics reviewed against PubMed: Akkermansia trials, the pasteurization paradox, marketing claims, red flags. Honest evidence gaps noted.
Collagen Peptides for Skin: What Actually Has Evidence?
2.5 g of a studied peptide beats 20 g of generic powder for skin. What Verisol trials measured, where ceramides fit, and the label traps that waste money.
Hair Loss After Weight Loss: What Actually Helps
Telogen shedding after rapid weight loss or GLP-1 treatment is common. Sort nutrition gaps, shedding triggers, and pattern hair loss before buying supplements.
Nutrafol vs Minoxidil: Which Actually Regrows Hair?
Minoxidil is FDA-approved with decades of regrowth data. Nutrafol rests on a manufacturer-sponsored RCT nobody replicated. When stacking them makes sense.
Supplements for SSRI-induced ED: what the evidence actually shows
SSRI-induced ED supplements reviewed against PubMed: saffron, L-citrulline, maca, plus yohimbine and ginkgo red flags. Evidence gaps noted.
Berberine vs Ozempic: What It Can and Cannot Do
Berberine missed its primary endpoint in the 2026 JAMA Network Open trial, so it is not 'natural Ozempic'. What the data still supports, and what it cannot do.
Ozempic Electrolytes: Dehydration, Fatigue & What Helps
Tiny meals and nausea on Ozempic drain sodium, potassium, and fluid. Compare electrolyte labels, sugar-free vs ORS, and when fatigue needs medical care.