Verified interaction concerns — supplement + medication pairs

Curated medication + supplement pairs with a documented mechanism — reviewed by a physician, graded by severity, never a safety clearance.

Educational lookup of documented interaction concerns — not a personalized safety check, not medical advice, and not a clearance to combine. Always confirm with your prescriber or pharmacist.

Check a combination

Pick a medication class and a supplement. Only reviewed combinations resolve — anything else stays an open question for your prescriber.

Prescription medication

Dietary supplement

This specific combination hasn't been reviewed yet.That does not mean it's safe — it means we don't have documented evidence either way. Ask your prescriber or pharmacist before combining.

Reviewed medication classes

How pairs are graded

MajorSignificant interaction — talk to your prescriber before combining.
ModerateDocumented concern — monitor and disclose to your clinician.
CautionLow-grade concern — timing, disclosure, or lab context.
Not reviewedAbsence from this base is not a safety statement — we never show a green "safe to combine" signal.

Each pair cites its evidence (PMIDs where they exist, or a stated pharmacology-standard basis) and carries a named reviewer with a verification date.