Your MUI
—
Waiting for inputs
0
5 · threshold
10+
Enter dose and years — MUI updates instantly.
Example: 2000 mg/day × 3 years → MUI 6
How to use this
- Daily dose — total metformin you take per day in milligrams (e.g. 2000 for two 1000 mg tablets).
- Years on metformin — approximate duration of continuous use.
- MUI > 5 — in Shivaprasad et al., higher deficiency odds; discuss serum B12 screening (± MMA if borderline) with your clinician. This tool does not diagnose deficiency.
Evidence context
This index comes from cohort work on metformin-associated B12 deficiency. ADA still recommends periodic B12 assessment after about 4–5 years on metformin, or sooner with anemia, neuropathy, dyspeptic symptoms, prior GI surgery, vegan diet, PPI use, or age 65+.