Educational reference of documented concerns — not a personalized safety check and not a clearance to combine. Confirm with your prescriber or pharmacist.
Reviewed supplements
- ModerateDOACs (apixaban, rivaroxaban, dabigatran, edoxaban)Garlic extract DOAC labels warn about bleeding with antiplatelet herbs; garlic inhibits platelet aggregation by changing platelet function. 1 PMIDverified 2026-08-18
- ModerateDOACs (apixaban, rivaroxaban, dabigatran, edoxaban)Ginkgo biloba The bleeding mechanism documented for ginkgo with warfarin applies without an INR to watch; DOAC monitoring is harder, which raises practical caution. 1 PMIDverified 2026-08-18
- CautionDOACs (apixaban, rivaroxaban, dabigatran, edoxaban)Panax ginseng (Korean red ginseng) Case reports describe INR changes and bleeding with ginseng on anticoagulants; without a warfarin-style INR window on DOACs, the practical level stays low-caution. 1 PMIDverified 2026-09-25
- CautionDOACs (apixaban, rivaroxaban, dabigatran, edoxaban)High-dose fish oil (3 g+ EPA+DHA per day) Antiplatelet effect of high-dose omega-3 adds to anticoagulation; the direct warfarin cohort found no significant signal, and no comparable DOAC-specific cohort exists. 1 PMIDverified 2026-08-18
Not in this list
A supplement missing from this list has not been reviewed against DOACs (apixaban, rivaroxaban, dabigatran, edoxaban) on this site. That is not a statement that combining it is safe.