Documented concern based on cited evidence — not a personalized safety check, not medical advice, and not a decision to combine or avoid. That decision belongs with your prescriber.
Significant interaction — talk to your prescriber before combining
Significant documented interaction. Talk to your prescriber before combining these two.
Mechanism and evidence
Ginkgo antagonists platelet-activating factor and case reports plus a large VA cohort show elevated bleeding signals (HR 1.38) with warfarin.
Evidence tier: cohort-case
The tier names the strongest cited study design. Some anchors studied the supplement on its own, or a related drug in the same class — in those pairs the grade rests on that evidence plus established pharmacology, as agreed with our medical reviewer.
What to discuss with your prescriber
- Do not combine ginkgo with warfarin unless your prescriber explicitly decides to.
- Any unusual bleeding is a same-day call.