Educational dose math only — not medical advice, not a product recommendation, and not a pass/fail on whether a supplement will work for you.
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Single-blind pilot; 95% CI not reported in primary paper.

Educational only — not medical advice. Disclaimer.

NIH DSLD market slice

Median3 g
Products2,818
Below32%

Bulk CSV dump 16 January 2026 · label entries through 2025. Disclosed amounts only — proprietary blends without gram weights excluded.

Trial floors

Primary

Cormio 2011 pilot (mild ED) · 1.5 g over 1 month (limited evidence) · Benefit shown — Single-blind pilot; 95% CI not reported in primary paper.

Label reading notes

  • Often sold as L-citrulline or citrulline malate — compare free citrulline equivalents when possible.
  • The direct ED trial used 1.5 g/day free-base citrulline for one month in mild vascular ED (n=24, single-blind). Higher shelf doses are pharmacokinetic extrapolation, not replicated erection outcomes.
  • Do not combine with PDE5 inhibitors or nitrates without clinician sign-off — additive blood-pressure effects are documented in supervised combination trials.