Educational dose math only — not medical advice, not a product recommendation, and not a pass/fail on whether a supplement will work for you.
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1.2 g per day of Kyolic aged garlic extract, standardized to S-allylcysteine, for three months in adults with hypertension (the GarGIC trial). Moved blood pressure, arterial stiffness, and inflammation-related markers in a modest, part-of-the-population way; earlier AGE trials showed clearer blood-pressure effects in hypertensive subgroups. Honest read: a real but modest cardiovascular-risk candidate, in one studied form.

Educational only — not medical advice. Disclaimer.

NIH DSLD market slice

Median0.4 g
Products366
Below99%

Bulk CSV dump 16 January 2026 · label entries through 2025. Disclosed amounts only — proprietary blends without gram weights excluded.

Trial floors

Primary

Aged garlic extract RCT (Ried 2018) · 1.2 g over 3 months (limited evidence · how we grade this) · Significant, low-quality evidence — 1.2 g per day of Kyolic aged garlic extract, standardized to S-allylcysteine, for three months in adults with hypertension (the GarGIC trial). Moved blood pressure, arterial stiffness, and inflammation-related markers in a modest, part-of-the-population way; earlier AGE trials showed clearer blood-pressure effects in hypertensive subgroups. Honest read: a real but modest cardiovascular-risk candidate, in one studied form.

Safety red flags

  • On warfarin, a DOAC, aspirin, or any antiplatelet drug: talk to the prescriber managing those drugs before adding a garlic extract.
  • Easy bruising, nosebleeds, or bleeding gums while using it: stop and call a clinician.

Label reading notes

  • Aged garlic extract is a specific preparation. Fresh garlic and generic garlic powder do not inherit this evidence.
  • The standardization marker is S-allylcysteine; a label without it is not the studied material, whatever the allicin math on the front.
  • On anticoagulants or antiplatelet drugs the pairing is a bleeding-risk conversation; tracked in our interaction base.