Documented concern based on cited evidence — not a personalized safety check, not medical advice, and not a decision to combine or avoid. That decision belongs with your prescriber.
Documented concern — monitor and disclose
Clinically relevant documented concern. Disclose the supplement to your clinician and keep monitoring in place.
Mechanism and evidence
Licorice-driven potassium loss increases digoxin toxicity risk; the narrow therapeutic window makes this a documented clinical concern.
Evidence tier: case-reports
The tier names the strongest cited study design. Some anchors studied the supplement on its own, or a related drug in the same class — in those pairs the grade rests on that evidence plus established pharmacology, as agreed with our medical reviewer.
What to discuss with your prescriber
- Do not take licorice while on digoxin.
- Tell your cardiologist about any licorice-containing supplement or tea.